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Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re.

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The rate of patients experiencing postTEAEs was similar in the placebo (25%) and galcanezumab groups (25% 120mg; 22% 240mg). The most common (>2%) postTEAEs were upper respiratory tract infections (viral and otherwise) but there was no difference between the originally assigned galcanezumab treatment arms and placebo.

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